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Calcifolinon 10

كالسيفولينون 10 | Chemotherapeutics and Drugs Affecting Immunoresponse

Drug Category	Immune system
Medicinal form	Vials
Active ingredient	Calcium Folinate
Concentration	10mg
Manufacturer	Global Ph. Ind.
Price	35 EGP

Uses

Mechansim:an antidote to folic acid antagonists, e.g. methotrexate , which block the conversion of folic acid to tetrahydrofolate by binding the enzyme dihydrofolate reductase,so reduce their haematological toxicities
Uses: to reduce the toxicity of the methotrexate ,Calcium folinate rescue is necessary when methotrexate is given at Doses exceeding 500 mg/m2 and should be considered with methotrexate Doses of 100 to 500 mg/m2.
Dosage: 15 mg folinic acid , given 12 to 24 hours after the beginning of methotrexate infusion. The same dose is given every 6 hours for 24 hours, initiall b intramuscular injection or intravenous injection or infusion.

Note: The information provided about this drug does not substitute for consulting a doctor.

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Calcifolinon 10

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