Calcium Folinate 100 mg/ 10 ml/ lg vial
Drug Category |
|
Medicinal form |
Vials |
Active ingredient |
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Concentration |
100mg |
Manufacturer |
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Price |
445 EGP |
Uses
Mechansim:an antidote to folic acid antagonists, e.g. methotrexate , which block the conversion of folic acid to tetrahydrofolate by binding the enzyme dihydrofolate reductase,so reduce their haematological toxicities
Uses: to reduce the toxicity of the methotrexate ,Calcium folinate rescue is necessary when methotrexate is given at Doses exceeding 500 mg/m2 and should be considered with methotrexate Doses of 100 to 500 mg/m2.
Dosage: 15 mg folinic acid , given 12 to 24 hours after the beginning of methotrexate infusion. The same dose is given every 6 hours for 24 hours, initiall b intramuscular injection or intravenous injection or infusion.
Note: The information provided about this drug does not substitute for consulting a doctor.
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38 EGPThe doctor answers your questions quickly
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